Brilique 60 mg and 90 mg film coated tablets - Summary of Product. Statins inhibit endogenous cholesterol production by competitive inhibition of HMG-Co A reductase (HMGCR), the enzyme that catalyzes conversion of HMG-Co A to mevalonate, an early rate-limiting step in cholesterol synthesis. "Pharmacogenomics Knowledge for Personalized Medicine" Clinical Pharmacology & Therapeutics (2012) 92(4): 414-417. No dose adjustment is necessary for patients with renal impairment see. have shown excretion of ticagrelor and its active metabolites in milk.
Crestor - FDA prescribing information, side effects and uses Brilique 60 mg twice daily is the recommended dose when an extended treatment is required for patients with a history of MI of at least one year and a hh risk of an atherothrombotic event (see section 5.1). Crestor official prescribing information for healthcare professionals. For patients with severe renal impairment CLcr 30 mL/min/1.73 m2 not on hemodialysis. The elimination half-life t1/2 of rosuvastatin is approximately 19 hours.
Crestor 5 mg - European Medicines Agency Marketed as Crestor, is a member of the drug class of statins, used in combination with exercise, diet, and weht-loss to treat hh cholesterol and related conditions, and to prevent cardiovascular disease. In 2013 Crestor was the fourth-hhest selling drug in the United States, accounting for approx. The effects of rosuvastatin on LDL cholesterol are dose-related. The use of. Crestor in patients with severe renal impairment is contraindicated for all doses. transporter is important in the hepatic elimination of rosuvastatin.
Crestor and route of elimination:
Rating: 100 / 100
Overall: 88 Rates